Advanced Light Microscopy Unit

Overview

The Advanced Light Microscopy Unit (ALMU) is a walk-in core unit on a mission to help, support and educate the research community from CRG and beyond to do quantitative bioimaging. We provide support on a range of technologies starting from experimental design, sample preparation, acquisition, bioimage analysis and visualization.

Our unit consists of microscope systems specifically designed for fluorescence microscopy ranging from widefield, and confocal to super-resolution systems and helps reveal structures from macro to the nanoscale. Together with our next-door neighbors, the Mesoscopic Imaging Facility (MIF) of the EMBL Barcelona, we cover the full spectrum of light microscopy and we collaborate to assist the scientific community in advancing their research. Click on the services tab to learn more about our support and how to gain access to our instruments.

You can learn more about the unit by taking the virtual tour HERE.

Latest Updates

 

	OMERO Workshop (7-8/11/2024) ALMU together with OME, the University of Dundee, and CRG's SIT & CRG training are organizing the OMERO workshop. This course will give a solid ground for CRG researchers and all researchers who would like to use the open-source image data management software to enable access, analysis, visualization, sharing, and publishing of microscopy data. This course is also an important milestone for CRG to start using CRG's OMERO server for image data management. For more information follow the link here.
	Spotlight on Jeremy Vincencio, Shoma Nakagawa & ALMU in Evident's innovative laser scanning confocal system brochure We are proud to see the fruit of our successful collaboration with Evident and ALMU users: Jeremy Vincencio's (Stroustrup Lab) and Shoma Nakagawa (Cosma Lab) in the brochure of Evident's new innovative laser scanning confocal system FLUOVIEW FV4000. Tests on the prototype were carried out at ALMU. For more information follow the link here.
	ALMU collaborates with a global initiative to promote reproducible microscopy data publishing (21/09/2023)
	ALMU collaborates to reveal the ancient origins of neurons (19/09/2023)

ALMU collaborates to test the new function Dynamic Profiler from Carl Zeiss 
We are proud to see the successful launch of the new function Dynamic Profiler which enables the measurement of molecular dynamics with spatial information. Tests were carried out at ALMU, with ALMU and ALMU users. For more information follow the link here.

Elyra 7 with Lattice SIM2 workshop with Carl Zeiss (27/03/2023)
ALMU hosted the Elyra 7 workshop that presents the latest advances allowing gentle imaging of cellular structure in the nanoscale, using SIM, PALM/STORM technologies at high speed with the ability to image deeper into the samples.  

February 27: Virtual seminar covering the ELyra 7 system capabilities and highlighting the super-resolution technology. Followed by a virtual live demo of the system.
February 27 - March 3: Hands-on demo with researcher's own samples.

Quantitative Light Microscopy Course (20-24/02/2023) ALMU together with the CRG training team is organizing the very first Quantitative LightMicroscopy Course. This unique course covers the entire spectrum of bioimaging, starting from the fundamental basis of optical microscopy, instrumentation, specimen preparation, molecular markers, right up to the most recent and revolutionary development in bioimaging and bioimage data analysis, including artificial intelligence in microscopy. For more information follow the link here.

IXplore SpinSR workshop with Evident/Olympus (04/05/2022)
ALMU hosted the IXplore SpinSR workshop that presented the latest advances in multi-modal confocal spinning disk imaging of live cells and tissues in super-resolution mode.
May 4: Virtual seminar covering the IXplore SpinSR system capabilities and highlighting the super-resolution technology. Followed by a virtual live demo of the system.
May 5 - May 18: Hands-on demo with researcher’s own samples.

CRG at the Dubai Expo Spain Pavilion (03/2022)
Nadia Halidi has joined forces with Neoalgae, an Austrian biotechnology company, and The Others TV, an animation studio based in Barcelona to showcase the potential of microalgae as a sustainable future solution. The movies were acquired with a high-speed camera using darkfield microscopy with components provided specifically for this project by Carl Zeiss Iberia S.L. The production was showcased in the Spain Pavilion at the Expo 2020 Dubai from October 2021 to March 2022.

Nadia Halidi CV

February 2021  Head of the Advanced Light Microscopy Unit, CRG, Barcelona, Spain.
2018 - 2021      Assistant manager, then manager of Micron Oxford Advanced Bioimaging Unit, University of Oxford, Oxford, UK. 
2017 - 2018      Postdoctoral researcher and imaging facility manager at the Botnar Research Center, University of Oxford, Oxford, UK.
2011 - 2015      Postdoctoral fellow at the Dept. of Cell Biology, Harvard Medical School, Boston, MA, USA.
2007 - 2011      PhD in Biophysics, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.  
2005                    Teaching assistant at the Kalamazoo College, Kalamazoo, MI, USA.
2002 - 2006      Research and teaching assistant at the Dept. of Biophysics, University of Pécs, Pécs, Hungary.