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CRG Scientific Sessions

CRG Scientific Sessions

10/12/201812:00MARIE CURIEPRBB-CRG SessionsMark L. SiegelCenter for Genomics and Systems Biology, Department of Biology, New York University, USA"Mechanisms controlling variation in yeast growth"Host: Ben Lehner (CRG)Abstract:
Genetically identical cells exhibit extensive phenotypic variation even under constant and benign conditions. This so-called nongenetic heterogeneity has important clinical implications: within tumors and microbial infections, cells show nongenetic heterogeneity in growth rate and in susceptibility to drugs or stress. The budding yeast, Saccharomyces cerevisiae, shows a similar form of nongenetic heterogeneity in which growth rate correlates...

12/12/201812:00PRBB AuditoriumGroup Leader SeminarsMiguel López BotetUPF"Survival strategies of microbial pathogens and reciprocal host defense adaptation"Host: Valcárcel Juárez, Juan

13/12/201812:00R_473.10_AULAPRBB Computational Genomics SeminarsLeila MansouriComparative Genomics, CRG (Notredame) / Functional Genomics unit, CNAG (Heath)Assessment of quality and reliability of Large-Scale Multiple Sequence Alignment¿Host: Garrido Enamorado, Romina

14/12/201812:00MARIE CURIEPRBB-CRG SessionsJuan Antonio VizcainoEuropean Bioinformatics Institute - EMBL-EBI, Cambridge, UK"Big data" approaches in proteomics: Big challenges give the best rewards"Host: Eduard Sabidó (CRG)Abstract:"Big data" approaches in proteomics: Big challenges give the best rewards
First of all, I will summarize the work we have done in the last years to create an infrastructure to enable data sharing of mass spectrometry (MS) proteomics data in the public domain, including the development of the world-leading PRIDE database (https://www.ebi.ac.uk/pride/), the related tools and software,...

17/12/201812:00MARIE CURIEPRBB-CRG SessionsLluis MoreyUniversity of Miami, Miller School of Medicine, Miami USA“Role of Polycomb complexes in breast cancer”Host: Luciano di Croce (CRG)

17/12/201815:00CHARLES DARWINCell and Developmental Biology ProgrammeEmanuele LeonciniHarvard University"Following single-cell physiology of bacteria through booms and busts"Host: Böke, ElvanAbstract:As microbes deplete local resources they undergo great changes in size, morphology, growth conditions and gene expression. Even in a clonal population, responses vary from cell to cell making it necessary to track individual cells along the bacterial growth curve. We developed a microfluidic platform for tracking >105 cell lineages in parallel even in dense and growing cultures with single-cell resolution under controlled conditions. We used this platform to study growth regimes along the growth curve, and to analyze strategies on how...

19/12/201812:00PRBB AuditoriumGroup Leader SeminarsJaume Bertranpetit, UPFIBE / CRG"The hidden information in the human genome: from function to evolution."Host: Valcárcel Juárez, Juan

11/01/201912:00MARIE CURIEPRBB-CRG SessionsTiziana BonaldiInstituto Europeo di Oncologia, Milan, IT"Protein modifications on and beyond histones, in health and disease: a proteomic perspective"Host: Eduard Sabidó (CRG)Abstract:Chromatin is a dynamic, well-organized and yet partially-defined protein-DNA-RNA structure that controls various DNA-dependent processes. A large number of site-specific post-translational modifications of histones (hPTMs) contribute to the maintenance and modulation of chromatin plasticity, gene activation, DNA replication and repair, and a variety of other biological processes and disease states. The observation of...

18/01/201912:00MARIE CURIEPRBB-CRG SessionsAlexander van OudenaardenHubrecht Institute, Utrech NL"Whole-organism clone-tracing using single-cell sequencing"Host: Ben Lehner (CRG)Abstract:Embryonic development is one of the most crucial periods in the life of a multicellular organism. A limited set of embryonic progenitors gives rise to all cells in the adult body. Determining which fate these progenitors acquire in adult tissue is a major challenge and requires the simultaneous measurement of clonal history and cell-type at single-cell resolution. Clonal history has traditionally been quantified by microscopically tracking cells during development...

08/02/201912:00MARIE CURIEPRBB-CRG SessionsCarl-Philipp HeisenbergInstitute of Science and Technology, AT"to be determined"Host: Verena Ruprecht (CRG)

15/02/201912:00MARIE CURIEPRBB-CRG SessionsClaudia BagniDépartment des neurosciences fondamentales, Université de Lausanne, CH"to be determined"Host: Juan Valcárcel (CRG)

15/03/201912:00MARIE CURIEPRBB-CRG SessionsJosé Luís Gomez-SkarmetaCentro Andaluz de Biología del Desarrollo (CABD), Sevilla, ES"to be determined"Host: Marc A. Marti-Renom (CRG) and Jorge Ferrer (CRG)

29/03/201912:00MARIE CURIEPRBB-CRG SessionsPascal HingampInstitut Méditerranéen d'Océanologie, Marseille, FR"to be determined"Host: Cedric Notredame (CRG)

12/07/201912:00MARIE CURIEPRBB-CRG SessionsTrisha WittkoppU-M LSA Ecology and Evolutionary Biology (EEB), USA"to be determined"Host: PhD Students

06/09/201912:00MARIE CURIEPRBB-CRG SessionsNathalie BalabanThe Hebrew University of Jerusalem, IL"to be determined"Host: Lucas Carey (UPF) and Ben Lehner (CRG)