PRBB-CRG Sessions
Scientific sessions of the PRBB centres funded by the Centre for Genomic Regulation (CRG) and the Barcelona Biomedical Research Park
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14/04/202312:00R_473.10_AULAPRBB-CRG SessionsGonçalo Castelo-BrancoLaboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden"Oligodendroglia during neural development and multiple sclerosis: insights from single-cell and spatial epigenomics"Host: Sergi ArandaAbstract:Professor Gonçalo Castelo-Branco is a Professor of Glial Cell Biology at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet, Stockholm, Sweden. Prof. Castelo-Branco received his PhD in Medical Biochemistry in 2005, working on development of dopaminergic neurons and neural stem differentiation. He...
21/04/202312:00MARIE CURIEPRBB-CRG SessionsSophie DumontDept. of Bioengineering and Therapeutic Sciences, Dept. of Biochemistry and Biophysics, UCSF, San Francisco, USA"Mechanics of the kinetochore-microtubule interface: mechanisms and functions"Host: Thomas SurreyAbstract:The kinetochore links chromosomes to spindle microtubules to drive chromosome segregation at cell division. While we know nearly all mammalian kinetochore proteins, how these give rise to the kinetochore’s emergent mechanics and function remains poorly understood. First, I will discuss our work probing how kinetochores can form microtubule attachments that are at once strong yet dynamic, two...
26/05/202312:00MARIE CURIEPRBB-CRG SessionsDavid M. GilbertLaboratory of Chromosome Replication and Epigenome Regulation, San Diego Biomedical Research Institute, CA, USA"Regulation of Replication Timing and Chromosome Architecture"Host: Roderic GuigóAbstract:The mammalian genome is replicated in a defined temporal sequence during S phase of each cell cycle known as the replication timing program. Since chromatin is assembled at the replication fork, and different types of chromatin are assembled at different times, replication timing is positioned to be central to maintenance or alteration of chromatin states. We have found that replication timing is a highly stable cell-type...
02/06/202312:00MARIE CURIEPRBB-CRG SessionsLiam HoltAssociate Professor, Institute for Systems Genetics, New York University School of Medicine, USA"Crowding, compression, and condensation"Host: Elvan BökeAbstract:Thousands of biochemical reactions occur simultaneously in the cell. Small molecules are channeled through metabolic pathways at blistering speed. Giant complexes assemble to orchestrate transcription and translation. ATP fuels the active transport of organelles along microtubules, and actin networks drive membrane remodeling and agitate the cytoplasm. All of this occurs within a crowded cell interior that approaches the physical limits where molecular jamming and...
16/06/202312:00MARIE CURIEPRBB-CRG SessionsHenrique Veiga-FernandesImmunophysiology Group, Champalimaud Centre for the Unknown, Lisbon, Portugal"tbd"Host: Pia Cosma
07/07/202312:00MARIE CURIEPRBB-CRG SessionsDirk SchubelerFMI, Basel, Switzerland"tbd"Host: Renee Beekman
15/12/202312:00MARIE CURIEPRBB-CRG SessionsCeline VallotInstitut Curie, Paris, France"tbd"Host: Renee Beekman