PRBB-CRG Sessions
Scientific sessions of the PRBB centres funded by the Centre for Genomic Regulation (CRG) and the Barcelona Biomedical Research Park
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23/10/202612:00MARIE CURIEPRBB-CRG SessionsElisa OricchioEPFL"TBC"Host: Renée Beekman
30/10/202612:00MARIE CURIEPRBB-CRG SessionsEmmanuel DeriveryMRC Laboratory of Molecular Biology"TBC"Host: Thomas Surrey & Adel Al Jord
06/11/202612:00PRBB AuditoriumPRBB-CRG SessionsNicola TernetteUniversity of Dundee"Redefining the HLA-E Immunopeptidome - a new landscape for therapeutic targeting"Host: Eduard SabidóAbstract:HLA-E is a non-classical HLA molecule with limited polymorphism, making it an attractive candidate for broadly applicable immunotherapeutic targeting. Its peptide repertoire, however, remains poorly understood. Using immunopeptidomics, machine-learning assisted prediction, and biochemical validation, we uncover an extended HLA-E immunopeptidome comprising canonical and non-canonical peptides, including cancer-associated ligands shared across individuals and tumour types....