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28
Nov
2022
Image 1. Mitotic spindles with microtubules (red) attached to chromosomes (blue) during cell division. Cells with normal TTLL11 function (right) have normal rates of microtubule polyglutamylation (green) while cells without TTLL11 (left) are unmodified. Isabelle Vernos
Cell division enzyme earmarked as potential new cancer therapeutic target

The enzyme’s activity was found to be compromised in human cancer cells

RESEARCH
27
Oct
2022
Image of a mouse pancreatic islet, regions in the pancreas that contain beta cells which secret insulin. The HASTER regulatory element has been knocked out in this mouse, resulting in changes to beta cell function that cause diabetes. Credit: Miguel A Garriga/
Diabetes-causing gene can be regulated like a rheostat

Studying noncoding RNAs opens new avenues to understand human disease 

RESEARCH
19
Oct
2022
Alterations to gut mucous may trigger ulcerative colitis

The findings pave the way for the development of routine medical tests that predict the onset of the disease before symptoms appear

RESEARCH
13
Oct
2022
MiOS captures how genes fold and work at unprecedented resolution

New genome imaging technique is “like upgrading from the Hubble to the James Webb” 

RESEARCH
29
Sep
2022
Biomarkers used to track benefits of anti-ageing therapies can be misleading

Dr. Nick Stroustrup's 'Lifespan Machine' questions the use of ageing biomarkers

RESEARCH
22
Aug
2022
Researchers show how mutations in ‘dark genome’ cause pancreatic malformations

Researchers solve paradox of how mutations in a single enhancer can be catastrophic

RESEARCH
12
Aug
2022
Inflammation protein found to have new role in embryonic development

IL-6 has been linked to diseases such as rheumatoid arthritis and severe COVID-19.

RESEARCH
03
Aug
2022
‘RNA fishing’ reveals new driver of melanoma malignancy and metastasis

PDIA6 represents a potential new therapeutic target to reduce spread of melanoma

RESEARCH
20
Jul
2022
Human eggs remain healthy for decades by putting ‘batteries on standby mode’

Study in Nature explains how cells remain dormant in ovaries without losing their reproductive capacity.
 

RESEARCH
14
Jul
2022
Metastatic breast cancer treatment funded by the ”la Caixa” Foundation

The CaixaResearch Validate grant will offer financial support and trainign in technology transfer

RESEARCH

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