Research
Research
12
Apr
2022
Act of sabotage determines mammalian embryonic development
Study finds evidence that the regulation of alternative splicing, which rarely goes wrong in healthy cells, goes haywire in an unexpected place.
06
Apr
2022
Abundant ‘secret doors’ on human proteins could reshape drug discovery
First maps of allosteric sites on human proteins could lead to safer, smarter and more effective medicines.
15
Mar
2022
Cell fusion ‘awakens’ regenerative potential of human retina
Fusing human retinal cells with adult stem cells could be a potential therapeutic strategy to treat visual impairment
08
Mar
2022
Researchers chart gene expression in endometrial cancer
Findings in study in eLife pinpoint to new diagnostic tools
03
Mar
2022
Fully functional pancreatic beta cells created from stem cells for the first time
Treating diabetes patients with these cells is “no longer in the realms of science fiction”
08
Feb
2022
Colorectal cancers raise defensive barrier in response to chemotherapy
Findings pave way to overcome drug-resistant colorectal cancer when pairing chemotherapy with mucin secretion inhibitors
11
Jan
2022
Researchers reveal how skin cells form a first line of defence against cancer
New insights into the molecular mechanisms that underpin natural defences against skin cancer
21
Dec
2021
Human nucleus transcription activity captured at unprecedented nanometric resolution
Newly transcribed RNA molecules are regulated in a more fine and precise way than previously thought
15
Dec
2021
One mutation or two? Researchers discover why some genes require one or two hits to promote cancer
This is the first time researchers have characterised the landscape of what are known as third-order interactions in cancer
14
Dec
2021
Immune cell atlas of human cancers created for precision oncology
The atlas can aid efforts to predict the immunotherapy response and prognosis of cancer in patients
Pages
Study finds evidence that the regulation of alternative splicing, which rarely goes wrong in healthy cells, goes haywire in an unexpected place.
First maps of allosteric sites on human proteins could lead to safer, smarter and more effective medicines.
Fusing human retinal cells with adult stem cells could be a potential therapeutic strategy to treat visual impairment
Findings in study in eLife pinpoint to new diagnostic tools
Treating diabetes patients with these cells is “no longer in the realms of science fiction”
Findings pave way to overcome drug-resistant colorectal cancer when pairing chemotherapy with mucin secretion inhibitors
New insights into the molecular mechanisms that underpin natural defences against skin cancer
Newly transcribed RNA molecules are regulated in a more fine and precise way than previously thought
This is the first time researchers have characterised the landscape of what are known as third-order interactions in cancer
The atlas can aid efforts to predict the immunotherapy response and prognosis of cancer in patients