Gebauer Lab

Gebauer LabGebauer Lab

Genome Biology

Gebauer Lab
RNA-binding proteins in cancer
Group leader

Gebauer Lab

RNA-binding proteins in cancer
Group leader

1990 PhD in Biological Sciences by the Department of Biochemistry and Molecular Biology, Autónoma University of Madrid, Spain.
1992-1996 Postdoctoral Research Associate in Joel D. Richter's laboratory, Worcester Foundation for Biomedical Research, Massachusetts, USA.
1996-2000 Postdoctoral Research Associate in Matthias W. Hentze's laboratory, European Molecular Biology Laboratory (EMBL), (Germany).
2001 Staff Scientist, European Molecular Biology Laboratory (EMBL), Germany.
2002 Group Leader at the Center for Genomic Regulation (CRG), Barcelona, Spain.
2021 Co-coordinator of the Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain.

News

CRG and IBEC to design new RNA therapeutics for brain disorders (11/01/2024)
Researchers at the Centre for Genomic Regulation (CRG) and the Institute for Bioengineering of Catalonia (IBEC) have received a BIST Ignite Grant to explore new ways of treating brain disorders using RNA technology. The award was announced today at the Barcelona Institute of Science and Technology (BIST) Forum, an event held at La Pedrera in Barcelona.

‘RNA fishing’ reveals new driver of melanoma malignancy and metastasis (03/08/2022)
Researchers at the CRG have identified several proteins involved in the progression of melanoma, the deadliest form of skin cancer.

Researchers reveal how skin cells form a first line of defence against cancer (11/01/2022)
A study published today in Cell Reports reveals important insights into the molecular mechanisms that underpin the body’s natural defences against the development of skin cancer.

CRG scientists will explore new treatments for Retinitis Pigmentosa and melanoma (25/07/2018)
La Caixa Banking Foundation announced today the 20 awarded projects in its 1st Health Research Call. The CRG will lead and host two of the twenty awarded projects out of the more than 780 projects that were submitted. CRG group leaders Maria Pia Cosma and Fátima Gebauer will receive funding to develop their projects, which will explore new treatments for retinal degeneration and melanoma metastasis and progression respectively.

Fátima Gebauer and Ben Lehner elected EMBO Members (16/06/2017)

Summary

Our group is interested in the regulation of mRNA translation by RNA-binding proteins (RBPs). This type of regulation is widely used in Biology to modulate processes such as metabolism, cell differentiation, embryonic patterning or synaptic transmission. We wish to understand the molecular mechanisms of translational control and the RNA networks that are established to maintain cell homeostasis. We are interested on how de-regulation of RBP function leads to disease, in particular to cancer.

Other information about the group

We acknowledge the financial contribution of the Spanish Ministry of Economy and Innovation, and the European Regional Development Fund (ERDF) to the development of the project “RNA binding proteins in translation and metastasis” (Ref. PGC2018-099697-B-I00). We also acknowledge the contribution of AGAUR (Ref. 2017SGR534), Marató-TV3 (Ref 201314), La Caixa Foundation (HR17-00232) and the Melanoma Research Alliance (Ref: 826530).