March 24th, 2022
9:10-9:45 "New genomic technologies to deconstruct cell identity in reprogramming and development"
Samantha Morris | Washington University in St. Louis
Session 1 - Single cell epigenomics and cancer
Chair: Lars Velten
9:50-10:15 "High-throughput targeted single-cell DNA methylation analysis for uncovering epigenetic heterogeneity"
Renee Beekman | Centre for Genomic Regulation (CRG)
10:15-10:40 "Decoding HIF pathway expression and therapeutic potential in human acute myeloid leukemia-initiating cells evolution using single-cell transcriptomics"
Juan Luis Trincado (Menendez's Lab) | Josep Carreras Leukaemia Research Institute (JCI)
10:40-11:05 "Atlasing Human Primary Immunodeficiencies"
Esteban Ballestar | Josep Carreras Leukaemia Research Institute (JCI)
11:05-11:25 "Unleashing the Power of Single-Cell Multi-Modal Analysis to Advance Precision Medicine"
Gema Fuerte, Senior European Field Application Scientist, Missio Bio (sponsored talk)
11:25-11:55 Coffee break
Session 2 - Single cell technology
Chair: Elisabetta Mereu
11:55-12:20 "Tumor immune cell mapping for next-generation pathology"
Holger Heyn | Centro Nacional de Análisis Genómico (CNAG-CRG)
12:20-12:40 "Unsupervised discovery of sub- and intercellular patterns of expression via deep generative modeling on spatial multi-omics data"
Luca Marconato | EMBL Heidelberg (contributed talk)
12:40-13:00 "Single-cell genome-plus-transcriptome sequencing without upfront genome preamplification reveals differential cell state plasticity and treatment response between genetic subclones"
Sebastiaan Vanuytven | KU Leuven (contributed talk)
13:00-13:20 "Resolving Spatial Heterogeneity Using Nanostring's High Precision and Single-Cell Profiling Platforms"
Niccolo Mariani | Technical Sales Specialist, NanoString Technologies (sponsored talk)
14:00-14:30 Special Workshop: "Open Science & Publishing Tips"
Novella Guidi | Life Science Alliance (EMBO Press, Rockefeller University Press, Cold Spring Harbor Laboratory Press)
Session 3 - Single cell perspectives on hematopoiesis
Chair: Renee Beekman
15:00-15:20 "Democratizing single cell research"
Thomas Osborne | Dolomite Bio | Izasa Scientific (sponsored talk)
15:20-15:45 "Transcriptional regulation of the trophectoderm-ICM bifurcation during pre-implantation embryo development"
Thomas Graf | Centre for Genomic Regulation (CRG)
15:45-16:05 "Single-cell multi-omics reveal routes of purifying selection and metabolic vulnerabilities due to pathogenic mitochondrial DNA"
Leif Ludwig | Berlin Institute of Health (contributed talk)
16:05-16:35 Coffee break
16:35-17:00 "Single-cell lineage analysis of aged and premalignant hematopoietic stem cells"
Alejo Rodriguez-Fraticelli | Institute for Research in Biomedicine (IRB Barcelona)
17:00-17:25 "Clonally resolved single-cell multi-omics enables the identification of cancer specific surface antigens"
Lars Velten | Centre for Genomic Regulation (CRG)
17:25-17:55 "Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics"
Adam Mead | University of Oxford
18:00-20:00 Social hour & Poster session
March 25th, 2022
Session 4 - Single cell genomics and human disease
Chair: Holger Heyn
9:00-09:25 "Heterotypic cell interactions direct neoplastic competence within the pre-malignant pancreas"
Direna Alonso | IRB Barcelona (contributed talk)
09:25-09:45 "Developmental origins of cell heterogeneity in the human lung"
Sergio Marco-Salas | Stockholm University (contributed talk)
09:45-10:10 "Single-cell multi-omics: from cell atlases to human diseases"
Elisabetta Mereu | Josep Carreras Leukaemia Research Institute (JCI)
10:10-10:45 "From genotype to phenotype with single-cell resolution"
Oliver Stegle | German Cancer Reseach Center
10:45-11:15 Coffee break sponsored by 10x Genomics
Session 5 - Single cell genomics and fundamental principles of biology
Chair: Alejo Rodriguez-Fraticelli
11:15-11:40 "Single cell approaches for compartive and regulatory characterization of major animal cell types"
Anamaria Elek (Sebé-Pedrós lab) | Centre for Genomic Regulation (CRG)
11:40-12:05 "Untangling the structure of gene regulatory networks during adaptation"
Mariona Nada-Ribelles (Posas' lab) | Institute for Research in Biomedicine (IRB Barcelona)
12:05-12:25 "New Perspectives in Single Cell: Pushing the Boundaries with 10x Genomics Solutions"
Christophe Fleury | 10xGenomics | Bonsai Lab (sponsored talk)
12:25-12:50 "Single-cell transcriptomics of iPSC-derived neurons reveals functional changes in Alzheimer's Disease"
Mireya Plass or lab member | Bellvitge Biomedical Research Institute (IDIBELL)
12:50-13:25 "Decoding the developing human immune system"
Muzz Haniffa | Newcastle University & Wellcome Sanger Institute
13:25-13:35 Closing remarks