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Single Cell Genomics Symposium

Single Cell Genomics SymposiumSingle Cell Genomics Symposium




Preliminary Program

March 24th, 2022

9:00-9:10 Welcome

9:10-9:45 "New genomic technologies to deconstruct cell identity in reprogramming and development"
                       Samantha Morris | Washington University in St. Louis

Session 1 - Single cell epigenomics and cancer
                      Chair: Lars Velten

9:50-10:15 "High-throughput targeted single-cell DNA methylation analysis for uncovering epigenetic heterogeneity"
                         Renee Beekman | Centre for Genomic Regulation (CRG) 

10:15-10:40 "Decoding HIF pathway expression and therapeutic potential in human acute myeloid leukemia-initiating cells evolution using single-cell transcriptomics"
                           Juan Luis Trincado (Menendez's Lab) | Josep Carreras Leukaemia Research Institute (JCI)  

10:40-11:05 "Atlasing Human Primary Immunodeficiencies"
Esteban Ballestar | Josep Carreras Leukaemia Research Institute (JCI) 

11:05-11:25 "Unleashing  the Power of Single-Cell Multi-Modal Analysis to Advance Precision Medicine"
                          Gema Fuerte, Senior European Field Application Scientist, Missio Bio (sponsored talk)

11:25-11:55 Coffee break

Session 2 - Single cell technology
                      Chair: Elisabetta Mereu

11:55-12:20 "Tumor immune cell mapping for next-generation pathology"
                          Holger Heyn | Centro Nacional de Análisis Genómico (CNAG-CRG) 

12:20-12:40 "Unsupervised discovery of sub- and intercellular patterns of expression via deep generative modeling on spatial multi-omics data"
Luca Marconato | EMBL Heidelberg (contributed talk)

12:40-13:00 "Single-cell genome-plus-transcriptome sequencing without upfront genome preamplification reveals differential cell state plasticity and treatment response between genetic subclones"
                          Sebastiaan Vanuytven | KU Leuven (contributed talk)

13:00-13:20 "Resolving Spatial Heterogeneity Using Nanostring's High Precision and Single-Cell Profiling Platforms"
                          Niccolo Mariani | Technical Sales Specialist, NanoString Technologies (sponsored talk)

13:20-15:00 Lunch

14:00-14:30 Special Workshop: "Open Science & Publishing Tips"
                          Novella Guidi | Life Science Alliance (EMBO Press, Rockefeller University Press, Cold Spring Harbor Laboratory Press)

Session 3 - Single cell perspectives on hematopoiesis
                      Chair: Renee Beekman

15:00-15:20 "Democratizing single cell research"
                          Thomas Osborne | Dolomite Bio | Izasa Scientific (sponsored talk)

15:20-15:45 "Transcriptional regulation of the trophectoderm-ICM bifurcation during pre-implantation embryo development"
                          Thomas Graf | Centre for Genomic Regulation (CRG) 

15:45-16:05 "Single-cell multi-omics reveal routes of purifying selection and metabolic vulnerabilities due to pathogenic mitochondrial DNA"
Leif Ludwig | Berlin Institute of Health (contributed talk)

16:05-16:35 Coffee break

16:35-17:00 "Single-cell lineage analysis of aged and premalignant hematopoietic stem cells"
                           Alejo Rodriguez-Fraticelli | Institute for Research in Biomedicine (IRB Barcelona) 

17:00-17:25 "Clonally resolved single-cell multi-omics enables the identification of cancer specific surface antigens"
                          Lars Velten | Centre for Genomic Regulation (CRG)

17:25-17:55 "Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics"
                         Adam Mead | University of Oxford

18:00-20:00 Social hour & Poster session


March 25th, 2022

Session 4 - Single cell genomics and human disease 
                      Chair: Holger Heyn

9:00-09:25 "Heterotypic cell interactions direct neoplastic competence within the pre-malignant pancreas"
                          Direna Alonso | IRB Barcelona (contributed talk)

09:25-09:45 "Developmental origins of cell heterogeneity in the human lung"
                          Sergio Marco-Salas | Stockholm University (contributed talk)

09:45-10:10 "Single-cell multi-omics: from cell atlases to human diseases"
Elisabetta Mereu | Josep Carreras Leukaemia Research Institute (JCI) 

10:10-10:45 "From genotype to phenotype with single-cell resolution"
                           Oliver Stegle | German Cancer Reseach Center

10:45-11:15 Coffee break sponsored by 10x Genomics

Session 5 - Single cell genomics and fundamental principles of biology
Chair: Alejo Rodriguez-Fraticelli

11:15-11:40 "Single cell approaches for compartive and regulatory characterization of major animal cell types"
Anamaria Elek (Sebé-Pedrós lab) | Centre for Genomic Regulation (CRG) 

11:40-12:05 "Untangling the structure of gene regulatory networks during adaptation" 
                           Mariona Nada-Ribelles (Posas' lab) | Institute for Research in Biomedicine (IRB Barcelona) 

12:05-12:25 "New Perspectives in Single Cell: Pushing the Boundaries with 10x Genomics Solutions"
                          Christophe Fleury | 10xGenomics | Bonsai Lab (sponsored talk)

12:25-12:50 "Single-cell transcriptomics of iPSC-derived neurons reveals functional changes in Alzheimer's Disease"
                           Mireya Plass or lab member | Bellvitge Biomedical Research Institute (IDIBELL)

12:50-13:25 "Decoding the developing human immune system"
                       Muzz Haniffa | Newcastle University & Wellcome Sanger Institute

13:25-13:35 Closing remarks

13:35-15:00 Lunch