Epigenetics key to daily production of 10 billion blood cells without mistakes
The epigenetic regulator Phf19 is essential for HSC differentiation, and in its absence blood tissue is imbalanced and equivalent to what naturally occurs with ageing.
RESEARCH
30
Jul
2020
Human body mostly composed of just five major groups of cell
The findings are complementary to the results of the third phase of the international ENCODE project
RESEARCH
28
Jul
2020
New genome mapper is like “upgrading from dial-up to fibre-optic”
The new technique images genomes more cheaply, more quickly and increases range of visibility compared to currently available methods
RESEARCH
08
Jul
2020
No evidence for a controversial type of mutation bias in the human germline
The findings lay to rest theories that past human germline studies estimating selection would have to be reassessed.
RESEARCH
08
Jun
2020
3-D shape of human genome essential for robust inflammatory response
The findings shed new light on the fundamental relationship between how a genome folds and the function of a cell
RESEARCH
02
Jun
2020
Charting metabolic maps in the pursuit of new vaccines and antimicrobials
The new methods are a useful tool for other researchers to quickly evaluate a microorganism’s active metabolism, boosting chances of finding new applications
RESEARCH
29
May
2020
Ready, set, action: new tools to film genome dynamics
No other experimental techniques available today can make these type of observations at this resolution
RESEARCH
19
May
2020
Secrets of the internal human cell cytoskeleton revealed
New insights into how human cells stimulate the production of microtubules, a fundamental building block of life.
RESEARCH
08
May
2020
New therapeutic targets for infertility and cancer revealed
CRG researchers share the result of the most comprehensive evolutionary analysis of RNA modification proteins to date.
RESEARCH
05
May
2020
New therapeutic targets for treating memory impairment in Down syndrome
Researchers reveal how brain alterations in mice with Down's syndrome respond to chronic treatment with a component of green tea.