PRBB-CRG Sessions
Scientific sessions of the PRBB centres funded by the Centre for Genomic Regulation (CRG) and the Barcelona Biomedical Research Park
 |
 |
 |
 |
 |
 |
10/04/202612:00MARIE CURIEPRBB-CRG SessionsGregory GibsonGeorgia Institute of Technology"Haplotype-Embedded Regulatory Variation Shapes Gene Expression and Immune Associations"Host: Arcadi NavarroAbstract:The regulation of gene expression is typically mediated by multiple independent associations each parsimoniously assumed to be due to the activity of a single causal variant. In this talk I will challenge this assumption by reporting results of experiments using expression CROPseq to fine-map regulatory potential for 4,382 SNPs in 87 loci associated with immune disease. An average of 2.3 variants contribute to each of 66 fine-mapped eQTL, with some cell-state...
16/04/202614:00MARIE CURIEPRBB-CRG SessionsJob DekkerUMass Chan Medical School"A pathway for formation of an RNA-mediated nuclear compartment"Host: Marc Marti-RenomAbstract:Mammalian nuclei are spatially compartmentalized so that active and inactive segments of the genome occupy separate sub-nuclear neighborhoods. Compartments are often found in association with nuclear structures such as the nuclear lamina, nucleoli, and nuclear speckles (speckles), suggesting links between them. The mechanisms by which compartments form remain largely unknown. Speckles are large nuclear bodies that contain high concentrations of RNA...
17/04/202612:00MARIE CURIEPRBB-CRG SessionsAtaman SendölInstitute for Regenerative Medicine (IREM), University of Zurich"Single-cell approaches for monitoring stem cells in aging, clonal expansion and cancer"Host: Fatima GebauerAbstract:Clonal expansions of stem cell populations are widespread in normal epithelia and can remodel entire tissues over a lifetime. However, how these clonal expansions impact tissue function and why only a small fraction of these expanded clones undergo malignant transformation remains poorly understood. In this talk, I will discuss our recent development of in vivo single-cell approaches to dissect stem cell behavior across clonal expansion, aging and...
15/05/202612:00MARIE CURIEPRBB-CRG SessionsAnders H. LundUniversity of Copenhagen"TBC"Host: Fatima Gebauer
22/05/202612:00MARIE CURIEPRBB-CRG SessionsFrancesca SpagnoliKing's College London"TBC"Host: Jorge Ferrer
01/06/202612:00MARIE CURIEPRBB-CRG SessionsDuncan OdomGerman Cancer Research Center (DKFZ)"The genetic mechanisms underlying mammalian germline and somatic evolution"Host: Donate WeghornAbstract:The Odom laboratory studies interdisciplinary questions bridging genetics, genome regulation, cancer biology, and evolution. In this talk, I will be providing a brief retrospective of our past 20 years of discoveries in genome evolution, along with related recent and unpublished stories. I will discuss the extensive and rapid turn-over of tissue-specific transcription factor binding, CTCF insulator elements, polymerase occupancies, and enhancer...
19/06/202612:00MARIE CURIEPRBB-CRG SessionsMichal Bassani-SternbergCentre Hospitalier Universitaire Vaudois, Université de Lausanne & Ludwig Cancer Research Center"TBC"Host: Eduard Sabidó
26/06/202612:00MARIE CURIEPRBB-CRG SessionsGuillaume AndreyUniversité de Genève"TBC"Host: Renée Beekman
03/07/202612:00MARIE CURIEPRBB-CRG SessionsMaria BarnaStanford Medicine"TBC"Host: Fatima Gebauer
04/09/202612:00MARIE CURIEPRBB-CRG SessionsTaro KitazawaDANDRITE-Nordic-EMBL & Aarhus University"TBC"Host: Hsiu-Chuan Lin
18/09/202612:00MARIE CURIEPRBB-CRG SessionsAugustine KongOxford Big Data Institute"TBC"Host: Amelie Baud
23/10/202612:00MARIE CURIEPRBB-CRG SessionsElisa OricchioEPFL"TBC"Host: Renée Beekman
30/10/202612:00MARIE CURIEPRBB-CRG SessionsEmmanuel DeriveryMRC Laboratory of Molecular Biology"TBC"Host: Thomas Surrey & Adel Al Jord
04/12/202612:00MARIE CURIEPRBB-CRG SessionsChristine MayrMemorial Sloan Kettering Cancer Center"TBC"Host: Adel Al Jord