PRBB-CRG Sessions Francesca Spagnoli

22/05/202612:00MARIE CURIEPRBB-CRG SessionsFrancesca SpagnoliKing's College London"Mapping progenitor niche dynamics for regulation of cell fate"Host: Jorge FerrerAbstract:The Spagnoli laboratory studies mechanisms regulating cell identity and plasticity in metabolic organs, such as the pancreas and liver. We use multimodal approaches in mouse embryos and human stem cell models to elucidate how distinct cell types arise from common progenitors and crosstalk to each other and surrounding microenvironment to acquire specialized shapes and to form functional organs. The long-term goal of our research is to translate developmental concepts into new therapies.