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PRBB-CRG Sessions

PRBB-CRG SessionsPRBB-CRG Sessions

Scientific sessions of the PRBB centres funded by the Centre for Genomic Regulation (CRG) and the Barcelona Biomedical Research Park


11/12/202012:00OnlinePRBB-CRG SessionsGeorg KustatscherUniversity of Edinburgh"Proteomic exploration of chromatin and gene expression"Host: Sara SdelciAbstract:In this seminar I will outline our efforts to explore aspects of chromatin biology by proteomics. I will present our method to enrich bulk chromatin for proteomic analyses and show how we used it to study the composition of chromatin - and how that changes as chromosomes condense during mitosis. In the second part of the talk I will introduce our work on the relationship between genome organisation and protein expression control. For example, in humans, 10% of protein-coding genes are transcribed from bidirectional...

18/12/202016:00OnlinePRBB-CRG SessionsCharles RotimiNational Human Genome Research Institute"to be defined"Host: Teresa D'Altri

29/01/202116:00OnlinePRBB-CRG SessionsArunag Verma; Chao ZhangUniversity of Pennsylvania"Global patterns of genetic variation at genes involved in SARS-CoV-2 infection, and association with clinical phenotypes relevant to COVID-19"Host: Teresa D'AltriAbstract:The COVID-19 pandemic caused by SARS-COV-2 infection has had a devastating impact on population health, with a disproportionate burden in minority populations. Transmission of the SARS-CoV-2 virus to humans requires its host receptor (i.e. ACE2) and other proteins in human host cells. We investigate nucleotide variation in genes that play a role in SARS-CoV-2 infection (ACE2, TMPRSS2, DDP4, and LY6E) in...