PRBB-CRG Sessions

12/06/202612:00MARIE CURIEPRBB-CRG SessionsMartin EilersBiozentrum Universität Würzburg"Role of non-canonical functions of MYC in oncogenesis"Host: Thomas GrafAbstract:MYC proteins are central oncogenes that contribute to the development of the majority of human cancers. They are classically viewed as DNA-bound transcription factors that regulate gene expression by forming heterodimers with the partner protein MAX. However, this canonical model does not readily explain several key oncogenic functions of MYC, such as its ability to promote immune evasion. In my talk, I will discuss the mechanisms by which pancreatic carcinoma evades...