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CRG Scientific Sessions

CRG Scientific SessionsCRG Scientific Sessions

03/02/202310:00MARIE CURIESystems Biology ProgrammeDr. Richard MottGenetic Institute, University College London"Dominance in Mammalian phenotypes and gene expression"Host: Baud, AmelieAbstract:Dominance in Mammalian phenotypes and gene expression

Richard Mott
Genetic Institute
University College London

Dominance arises from the interaction between different alleles within the same genomic locus, and historically played a major role in quantitative genetics. However, today most genome-wide association studies (GWAS) ignore dominance effects and assume alleles act additively. Here, we systematically investigated both dominance and additive effects across numerous physiological and gene expression traits of...

14/02/202315:00MARIE CURIEOther SeminarsAngus I. LamondCentre for Gene Regulation & Gene Expression, School of Life Sciences, University of Dundee, UK"tbd"

15/02/202312:00R_473.10_AULACell and Developmental Biology ProgrammeDr. Ignasi RoigFacultat de Biocències I Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona.“Mechanisms that regulate the ovarian reserve in mammals”Host: Böke, ElvanAbstract:Most reproduction problems in western societies are linked to women's fertility declines with age. This is partly caused by how mammalian eggs are formed. Women are born with a limited pool of follicles containing future eggs. This so-called ovarian reserve will be used during every woman's reproductive lifespan to produce fertilizable eggs. Thus, female fertility ends once this pool of follicles falls below a certain threshold (in humans, ~1000 primordial follicles)....

23/02/202315:00UPFSystems Biology ProgrammeXavier HernándezSerrano Lab."Translational control by differential expression of tRNAs"Host: Bartomeus Cistaré, Magalí

03/03/202312:00MARIE CURIEPRBB-CRG SessionsKonrad HochedlingerMassachusetts General Hospital / Harvard Medical School, Boston, USA"tbd"Host: Bernhard Payer

08/03/202312:00R_473.10_AULAGene Regulation,Stem Cells&Cancer Progr.Dr Pradeepa MadapuraBlizard Institute, Queen Mary University of London"Role of H4K16ac in the regulation of vertebrate genome"Host: Payer, Bernhard

10/03/202312:00MARIE CURIEPRBB-CRG SessionsAndrea CalifanoColumbia University Medical Center, Herbert Irving Cancer Research Center, New York, USA"Bringing single cell analyses to the clinics"Host: Pia CosmaAbstract:We have developed network-based methodologies for the systematic identification, validation, and pharmacological targeting of a new class of therapeutic targets. These targets comprise Master Regulator proteins, whose concerted activity within a Regulatory Checkpoint module is responsible for the mechanistic implementation and maintenance of cell transcriptional state, in both transformed and non-transformed cells. By leveraging these methodologies, we have...

17/03/202312:00MARIE CURIEPRBB-CRG SessionsCarsten JankeInstitut Curie, Paris, France"tbd"Host: Thomas Surrey

14/04/202312:00R_473.10_AULAPRBB-CRG SessionsGonçalo Castelo-BrancoKarolinska Institutet, Stockholm, Sweden"tbd"Host: Sergi Aranda

21/04/202312:00MARIE CURIEPRBB-CRG SessionsSophie DumontDept. of Bioengineering and Therapeutic Sciences, Dept. of Biochemistry and Biophysics, UCSF, San Francisco, USA"tbd"Host: Thomas Surrey

26/05/202312:00MARIE CURIEPRBB-CRG SessionsDavid M. GilbertLaboratory of Chromosome Replication and Epigenome Regulation, San Diego Biomedical Research Institute, CA, USA"tbd"Host: Roderic Guigó

07/07/202312:00MARIE CURIEPRBB-CRG SessionsDirk SchubelerFMI, Basel, Switzerland"tbd"Host: Renee Beekman

15/12/202312:00MARIE CURIEPRBB-CRG SessionsCeline VallotInstitut Curie, Paris, France"tbd"Host: Renee Beekman