PRBB-CRG Sessions
Scientific sessions of the PRBB centres funded by the Centre for Genomic Regulation (CRG) and the Barcelona Biomedical Research Park
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20/09/201912:00MARIE CURIEPRBB-CRG SessionsSalvador AznarInstitute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain"Stem cell function in homeostasis and aging: why time and what we eat matter"Host: Juan Valcárcel (CRG)Abstract:We study how adult stem cells maintain tissue homeostasis, and why and how their striking regenerative capacity is altered during aging and cancer. One aspect we are particularly interested in is the fact that the activity of adult stem cells is under robust circadian control. This not only allows stem cells to anticipate correct functions according to the time of the day, but also to temporally segregate...
30/09/201912:00MARIE CURIEPRBB-CRG SessionsTatjana Sauka-SpenglerMRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, UK"Reverse engineering of the global Neural Crest Gene Regulatory Network in vivo"Host: Berta Alsina (UPF)
04/10/201912:00MARIE CURIEPRBB-CRG SessionsJoana LoizouResearch Center for Molecular Medicine of the Austrian Academy of Sciences, AT"Safeguarding the integrity of the human genome"Host: Sara Sdelci (CRG)Abstract:The human genome is constantly exposed to endogenous and exogenous sources of DNA damage. DNA repair pathways ensure that all resulting damage is efficiently removed hence maintaining the integrity of large eukaryotic genomes, by minimising the mutation rate. This is achieved through several highly effective pathways for DNA repair with distinct specificities, despite partial redundancies. The importance of these pathways is highlighted by the...
07/10/201912:00MARIE CURIEPRBB-CRG SessionsAndreas StrasserWEHI Australia"to be determined"Host: Ana Janic (UPF)
11/10/201912:00MARIE CURIEPRBB-CRG SessionsNorman DaveyUniversity College Dublin, IE"Understanding the functional role of the intrinsically disordered proteome"Host: Cedric Notredame (CRG)Abstract:Many proteins harbour extensive regions that lack stable secondary or tertiary structure in their native unbound states. These protein segments, known as intrinsically disordered regions (IDRs), are predicted to constitute up to 40% of the residues in higher eukaryotic proteomes. IDRs engage in diverse sets of activities that include providing enzyme docking sites regulating protein modification states, controlling protein stability (by recruiting ubiquitin ligases), acting...
18/10/201912:00MARIE CURIEPRBB-CRG SessionsYoshihide HayashizakiPreventive Medicine and Diagnosis Innovation Program RIKEN, JP"to be determined"Host: Roderic Guigó (CRG)
08/11/201912:00MARIE CURIEPRBB-CRG SessionsCarl-Phillip HeinsenbergIST Austria"to be determined"Host: Verena Ruprecht (CRG)
11/11/201912:00MARIE CURIEPRBB-CRG SessionsMike FeoloNational Center for Biotechnology Information, US"dbGaP: Data and Data processing"Host: Jordi Rambla (CRG)Abstract:The National Center for Biotechnology Information (NCBI) database of Genotypes and Phenotypes (dbGaP) provides unprecedented access to very large genetic and phenotypic datasets funded by the U.S. National Institutes of Health, and other funding agencies worldwide. Through controlled access, approved researchers from across the globe may obtain access to complete statistical analyses, individual phenotype information and molecular data. This presentation will summarize the data content, technical and biological...
18/11/201912:00MARIE CURIEPRBB-CRG SessionsNaama BarkaiWeizmann Institute of Science, IL"to be determined"Host: Postdoc students
22/11/201912:00MARIE CURIEPRBB-CRG SessionsPhilippe SanseauHead Computational Biology, GSK, UK"Use of highly-dimensional genetics and genomics data for drug discovery"Host: Roderic Guigó (CRG)Abstract:Drug discovery and development remains a very long and costly process. The majority of projects will fail due to lack of efficacy or because of safety concerns. This could happen at multiple stages but the later it is, the more expensive is the failure. Therefore, the choice of drug targets is very important since the outcome might not be known for many years. We have shown that using human genetics information may increase the chance of success in the clinic for new drug targets. In addition, the new functional genomics technologies...
25/11/201912:00MARIE CURIEPRBB-CRG SessionsAshby J. MorrisonDepartment of Biology, Stanford Biology, US"Epigenetic Regulation of Carcinogen Susceptibility"Host: Ben Lehner (CRG)Abstract:The development of many sporadic cancers is directly initiated by carcinogen exposure. Despite this knowledge, there has been remarkably little investigation into the factors that regulate susceptibility to acquire carcinogen-induced DNA lesions. Our research identifies the epigenetic regulators of carcinogen susceptibility and establish it as an origin of genome instability that mirrors mutagenesis in cancer.
29/11/201912:00MARIE CURIEPRBB-CRG SessionsInbal GoshenThe Edmond & Lily Safra, Centre for Brain Sciences, The Hebrew University of Jerusalemto be determinedHost: Mara Dierssen (CRG)
13/12/201912:00MARIE CURIEPRBB-CRG SessionsJitu MayorNational Centre for Biological Sciences, Bangalore, India"to be determined"Host: Vivek Malhotra (CRG)
16/12/201912:00MARIE CURIEPRBB-CRG SessionsCédric BlanpainWELBIO, Laboratory of Stem Cells and Cancer, Université Libre de Bruxelles, BE"to be determined"Host: Antoni Celià Terrassa (IMIM)
17/01/202012:00MARIE CURIEPRBB-CRG SessionsGunter MeisterUniversity of Regensburg, DEto be determinedHost: Fátima Gebauer (CRG)
24/01/202012:00MARIE CURIEPRBB-CRG SessionsIgor UlitskyWeizmann Institute of Science, Rehovot, IL"Functions and modes of action of long noncoding RNAs in mammalian cells"Host: Jorge FerrerAbstract:We are interested in understanding the codes that drive the functions of long noncoding RNAs (lncRNAs) in mammalian cells. It is now well appreciated that the human genome encodes tens of thousands of distinct lncRNA transcripts, and an increasing number are implicated as regulators in critical pathways in health and disease. The mechanisms underlying their activity, to what extent these rely on specific sequences or structures, and how they are...
31/01/202012:00MARIE CURIEPRBB-CRG SessionsNicole SoranzoWellcome Sanger Institute, Hinxton, UK"to be determined"Host: Roderic Guigó
21/02/202012:00MARIE CURIEPRBB-CRG SessionsSimon AlbertiMax Planck Institute of Molecular Cell Biology and Genetics (MPI-CBd), Dresden, Germany"to be determined"Host: Sebastian Maurer
28/02/202012:00MARIE CURIEPRBB-CRG SessionsMichael KieblerBioMedizinisches Centrum, Lehrstuhl Zellbiologie (Anatomie III), LMU, Martinsried, Germany"to be determined"Host: Fátima Gebauer and Sebastian Maurer
06/03/202012:00MARIE CURIEPRBB-CRG SessionsHeiko LickertHelmholtz Zentrum München GmbH, Institute of Diabetes & Regeneration Research, Helmholtz Diabetes Centre, Germany"to be determined"Host: Jorge Ferrer
13/03/202012:00MARIE CURIEPRBB-CRG SessionsRab PrinjhaVP, Head of Epinova Epigenetics DPU, VP Head of Epigenetics DPU (Immuno- and Cancer-Epigenetics), GlaxoSmithKline, UK"to be determined"Host: Luciano Di Croce
20/03/202012:00MARIE CURIEPRBB-CRG SessionsErin ShcumanMax Planck Institute for Brain Research, Frankfurt, DE"to be determined"Host: Juan Valcárcel
27/03/202012:00MARIE CURIEPRBB-CRG SessionsJames HackettEMBL Rome, IT"to be determined"Host: CRG PhD Students
03/04/202012:00MARIE CURIEPRBB-CRG SessionsIñigo MartincorenaWellcome Sanger Institute, Hinxton, UK"to be determined"Host: CRG PhD Students
16/10/202012:00MARIE CURIEPRBB-CRG SessionsAnne Ferguson-SmithUniversity of Cambridge. Department of Genetics"to be determined"Host: Bernhard Payer