PRBB-CRG Sessions

17/10/202512:00MARIE CURIEPRBB-CRG SessionsMichael HillerSenckenberg Research InstituteLinking phenotypic differences between species to differences in their genomesHost: Manuel IrimiaAbstract:In the first part of the talk, I will present TOGA (Tool to infer Orthologs from Genome Alignments) version 2.0, the completely reimplemented successor to the original method that simultaneously annotates coding genes and infers orthologs. TOGA 2.0 provides several new features, among them deep learning-based splice site predictions, which enable the method to cope with exon boundary shifts and evolutionary exon-intron structure changes.

In the second and third parts, I...