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CRG Scientific Sessions

CRG Scientific SessionsCRG Scientific Sessions

01/03/202412:00MARIE CURIEPRBB-CRG SessionsMarcelo GuerínInstitute of Molecular Biology of Barcelona, IBMB-CSIC"Sculpting therapeutic monoclonal antibody N-glycans using endoglycosidases"Host: Carlo CarolisAbstract:Immunoglobulin G (IgG) monoclonal antibodies are a prominent and expanding class of therapeutics used for the treatment of diverse human disorders. The chemical composition of the N-glycan on the fragment crystallizable (Fc) region determines the effector functions through interaction with the Fc gamma receptors and complement proteins. The chemoenzymatic synthesis using endo-beta-N-acetylglucosaminidases (ENGases) emerged as a strategy to obtain...

07/03/202412:00R_473.10_AULAPRBB Computational Genomics SeminarsClaudia VasalloEGATBCHost: Carbonell García, Rut

08/03/202412:00MARIE CURIEPRBB-CRG SessionsAdrian BrackenSmurfit Institute of Genetics, Trinity College Dublin"Interplay between PRC2 subcomplexes and canonical PRC1 in Development and Disease"Host: Luciano di CroceAbstract:In 2021, Professor Bracken was elected an EMBO Member for outstanding achievement in the life sciences. Since 2008, his lab has made several seminal discoveries in the field of chromatin and cancer biology. In particular, they provided key contributions to the understanding of the molecular mechanisms of how Polycomb Repressive Complexes regulate cell-fate decisions in stem cells and in cancer, e.g. Conway et al., Molecular Cell, 2018 and Healy et al. and...

15/03/202412:00MARIE CURIEPRBB-CRG SessionsDouglas BlackUniversity of California, Los Angeles (UCLA)"Alternative splicing regulation through interactions with the U2 snRNP"Host: Juan Valcárcel

26/03/202412:00MARIE CURIEPRBB-CRG SessionsKivanç BirsoyRockefeller University"tbc"Host: Elvan Böke

26/03/202412:00RAMÓN Y CAJALGene Regulation,Stem Cells&Cancer Progr.Prof. Donald C. RioUniversity of California at Berkeley"Neurodegenerative Diseases, RNA Binding Proteins and Alternative pre-mRNA Splicing"Host: Valcárcel Juárez, Juan

03/05/202412:00MARIE CURIEPRBB-CRG SessionsJoshua BrickmanNovo Nordisk Foundation Center for Stem Cell Medicine, reNEW Copenhagen"tbc"Host: Sergi Aranda

10/05/202412:00MARIE CURIEPRBB-CRG SessionsSteven GygyHarvard Medical School"tbc"Host: Eduard Sabidó

17/05/202412:00MARIE CURIEPRBB-CRG SessionsFrank BradkeDZNE German Center for Neurodegenerative Diseases"tbc"Host: Thomas Surrey