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CRG Scientific Sessions

CRG Scientific Sessions

28/02/202012:00MARIE CURIEPRBB-CRG SessionsMichael KieblerBioMedizinisches Centrum, Lehrstuhl Zellbiologie (Anatomie III), LMU, Martinsried, Germany"The role of RNA-binding proteins in learning and memory from the perspective of a cell biologist"Host: Fátima Gebauer and Sebastian MaurerAbstract:Targeting of mRNAs to synapses and the subsequent regulation of local synaptic translation are essential for hippocampal synaptic plasticity and for learning and memory. A set of RNA-binding proteins (RBPs), amongst others the brain-specific double-stranded RBP Staufen2 (Stau2) and Pumilio2 (Pum2) critically contribute to these processes. However, the...

28/02/202014:00R_473.10_AULASystems Biology ProgrammeJulian KönigInstitute of Molecular Biology (IMB), Mainz"Genomic views of the RNA world"Host: Lehner, BenAbstract:Our work focusses on deciphering the regulatory code of splicing and quality control mechanisms in human physiology and disease. To this end, we build on the iCLIP technology to map protein-RNA interaction sites throughout the transcriptome. We have set up ´in vitro iCLIP´ that combines the strength of biochemical experiments with the power of high-throughput sequencing, and we developed a massively parallel reporter screen to identify all cis-regulatory elements that control selected splicing decisions. This experimental setup enables us to obtain mechanistic insights...

02/03/202012:00MARIE CURIEPRBB-CRG SessionsLevi WaldronCUNY Graduate School of Public Health and Health PolicyMulti-omic analysis of subtype evolution and heterogeneity in high grade serous ovarian carcinomaHost: Robert Castelo

06/03/202012:00MARIE CURIEPRBB-CRG SessionsIgor UlitskyWeizmann Institute of Science, Rehovot, IL"Functions and modes of action of long noncoding RNAs in mammalian cells"Host: Jorge FerrerAbstract:We are interested in understanding the codes that drive the functions of long noncoding RNAs (lncRNAs) in mammalian cells. It is now well appreciated that the human genome encodes tens of thousands of distinct lncRNA transcripts, and an increasing number are implicated as regulators in critical pathways in health and disease. The mechanisms underlying their activity, to what extent these rely on specific sequences or structures, and how they are...

09/03/202012:00MARIE CURIEPRBB-CRG SessionsAndrea CalifanoColumbia University"Elucidating and targeting mechanisms of single cell state maintenance: from N of 1 to N of 1 of 1 studies"Host: Maria Pia CosmaAbstract:We have developed network-based methodologies for the systematic identification, validation, and pharmacological targeting of a new class of therapeutic targets. These targets comprise Master Regulator proteins, whose concerted aberrant activity within tightly regulated modules (tumor checkpoints) is responsible for the mechanistic implementation and maintenance of specific tumor cell states. By leveraging these methodologies, we have developed NY CLIA certified...

13/03/202012:00MARIE CURIEPRBB-CRG SessionsRab PrinjhaVP, Head of Epinova Epigenetics DPU, VP Head of Epigenetics DPU (Immuno- and Cancer-Epigenetics), GlaxoSmithKline, UK"Drugging Transcription: Progress and Potential for Treating Human Diseases"Host: Luciano Di Croce

20/03/202012:00MARIE CURIEPRBB-CRG SessionsErin SchumanMax Planck Institute for Brain Research, Frankfurt, DE"to be determined"Host: Juan Valcárcel

27/03/202012:00MARIE CURIEPRBB-CRG SessionsJames HackettEMBL Rome, IT"to be determined"Host: CRG PhD Students

03/04/202012:00MARIE CURIEPRBB-CRG SessionsIñigo MartincorenaWellcome Sanger Institute, Hinxton, UK"to be determined"Host: CRG PhD Students

17/04/202012:00MARIE CURIEPRBB-CRG SessionsMontserrat EliasUniversidad de Murcia"Bacterial “vision” and how its study unmasked a long-sought human enzyme"Host: Vivek MalhotraAbstract:Light is a crucial environmental signal and energy source that determines many metabolic, developmental and behavioral processes in most living organisms. It also causes photooxidative stress and cellular damage by generating highly reactive oxygen species like singlet oxygen, which attack cellular proteins, DNA and lipids. We study the molecular mechanisms by which the Gram-negative, predatory soil bacterium Myxococcus xanthus responds to light and their evolutionary conservation from bacteria to...

20/04/202012:00MARIE CURIEPRBB-CRG SessionsCecilia MoensFred Hutchinson Cancer Research Center, Seattle"to be determined"Host: Cristina Pujades

27/04/202012:00MARIE CURIEPRBB-CRG SessionsMehmet SomelUniversity of AnkaraThe diverse mechanisms of aging through the lents of transccriptomicsHost: Arcadi Navarro

08/05/202012:00PRBB AuditoriumPRBB-CRG SessionsMichael N. HallBiozentrum, University of Basel"to be determined"Host: Vivek Malhotra

11/05/202012:00PRBB AuditoriumPRBB-CRG SessionsGiovanni MarsicanoInserm
"to be determined"Host: Arnau Busquets

15/05/202012:00PRBB AuditoriumPRBB-CRG SessionsMarino ZerialMax Planck Institute of Molecular Cell Biology and Genetics, MPI-CBG"Self-organization and biomechanical properties of the endosomal membrane"Host: Vivek MalhotraAbstract:Our work has highlighted the function of Rab GTPases as key components for the biogenesis, transport and function of cellular membrane organelles. The functional characterization of the endosomal Rab5 machinery using biochemical and biophysical approaches has revealed new properties for the self-organization and mechanics of the endosomal membrane. Endosomes are important organelles for the...

18/05/202012:00PRBB AuditoriumPRBB-CRG SessionsAndres HidalgoCNIC, Madrid"to be determined"Host: Ruben Vicente

25/05/202012:00R_473.10_AULACell and Developmental Biology ProgrammeFaraz MardakhehCentre for Cancer Cell & Molecular Biology-Barts Cancer InstituteSubcellular mRNA localization regulates ribosome biogenesis in migrating cellsHost: Benito Mestres, Marta

08/06/202012:00PRBB AuditoriumPRBB-CRG SessionsAndrea MiglianoDepartment of Anthropology of the University of Zurich"to be determined"Host: Jaume Bertranpetit

15/06/202012:00PRBB AuditoriumPRBB-CRG SessionsFernando RacimoUniversity of CopenhaguenNew models to disentangle complex spatiotemporal patterns of adaptationHost: Carles Lalueza

22/06/202012:00PRBB AuditoriumPRBB-CRG SessionsSarah SchaackReed College, Department of Biology, Portland State University"to be determined"Host: Josefa González

26/06/202012:00PRBB AuditoriumPRBB-CRG SessionsMorten NielsenDTU Health Tech"to be determined"Host: Roderic Guigó

29/06/202012:00PRBB AuditoriumPRBB-CRG SessionsBen SteventonDepartment of Genetics of the University of Cambridge"to be determined"Host: Jordi García Ojalvo

10/07/202012:00MARIE CURIEPRBB-CRG SessionsHeiko LickertHelmholtz Zentrum München GmbH, Institute of Diabetes & Regeneration Research, Helmholtz Diabetes Centre, Germany"to be determined"Host: Jorge Ferrer

13/07/202012:00PRBB AuditoriumPRBB-CRG SessionsArn van den MaagdenbergDepartment of Human Genetics and Neurology, Leiden University Medical Centre (LUMC), The Netherlands"to be detemrined"Host: José M Fernández

17/07/202012:00PRBB AuditoriumPRBB-CRG SessionsBenoit BruneauGladstone Institute of Cardiovascular Disease"to be determined"Host: Thomas Graf

20/07/202012:00PRBB AuditoriumPRBB-CRG SessionsKate SutherlandThe Walter and Eliza Hall Institute of Medical Research"to be determined"Host: Ana Janic

03/09/202012:00PRBB AuditoriumPRBB-CRG SessionsKathryn WellenUniversity of Pennsylvania"to be determined"Host: Sara Sdelci

02/10/202012:00MARIE CURIEPRBB-CRG SessionsUlrich TechnauUniversity of Vienna"to be determined"Host: Arnau Sebé-Pedrós

05/10/202012:00MARIE CURIEPRBB-CRG SessionsPablo PelegrinInstituto Murciano de Investigación Biosanitaria IMIB-Arrixaca"to be determined"Host: José Yélamos

16/10/202012:00MARIE CURIEPRBB-CRG SessionsAnne Ferguson-SmithUniversity of Cambridge. Department of Genetics"to be determined"Host: Bernhard PayerAbstract:

20/11/202012:00MARIE CURIEPRBB-CRG SessionsMartin VingronMax Planck Institute for Molecular Genetics·to be determined"Host: Donate Weghom