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PRBB-CRG Sessions

PRBB-CRG Sessions

Scientific sessions of the PRBB centres funded by the Centre for Genomic Regulation (CRG) and the Barcelona Biomedical Research Park


04/09/201512:00MARIE CURIEPRBB-CRG SessionsSebastian LeidelMax Planck Research Group for RNA Biology, Max Planck Institute for Molecular Biomedicine, Münster DE"Getting the speed right - Links between RNA and protein quality control"Host: Juana Díez (UPF)Abstract:Proteins start to fold as they emerge from translating ribosomes. The kinetics of ribosome transit along a given mRNA can influence nascent chain folding, but the extent to which individual codon translation rates impact proteome integrity remains unknown. Here we show that slower decoding of distinct codons profoundly impairs protein homeostasis and elicits widespread protein...

07/09/201512:00MARIE CURIEPRBB-CRG SessionsJe LeeCSH Cold Spring Harbor Laboratory, New York US"Using fluorescent in situ sequencing (FISSEQ) to link genetic, phenotypic, and microenvironmental traits in cancer cell evolution"Host: Ben Lehner (CRG)Abstract:Identifying cancer-causing variants from functionally neutral variants is one of central aims in cancer biology; however, most oncogenic pathways can be potentiated or suppressed in a context-specific manner. To understand how cellular metabolism, epigenetics, and tissue microenvironment affects cellular evolution and tumor progression, we developed methods to visualize and quantify genetic, epigenetic, and...

14/09/201512:00MARIE CURIEPRBB-CRG SessionsCaren NordenMax Plank Institute of Molecular Cell Biology and Genetics (MPI-CBG)"to be determined"Host: Cristina Pujades (UPF)Abstract:The overall goal of the research in the Norden lab is to understand the cell biology and mechanisms that drive vertebrate morphogenesis. We use the process of vertebrate eye formation as a paradigm for how complicated morphogenetic events lead to the orchestrated formation of a complex neuronal tissue. Our model organism of choice is the teleost zebrafish as it represents the most suitable vertebrate for live imaging in combination with physical and genetic...

18/09/201512:00MARIE CURIEPRBB-CRG SessionsXavier TrepatInstitute for Bioengineering for Catalonia, Barcelona, Spain"to be determined"Host: Antonio García de Herreros (IMIM)

21/09/201512:00MARIE CURIEPRBB-CRG SessionsFrançois GuillemotMolecular Neurobiology, MRC National Institute for Medical Research, London UK"Signals and factors regulating stem cell activity in the adult brain"Host: Berta Alsina (UPF)

02/10/201512:00MARIE CURIEPRBB-CRG SessionsLuca MalcovatiDipartimento di Medicina Molecolare, Univesità degi Studi di Pavia"to be determined"Host: Lourdes Florensa (IMIM)

05/10/201512:00MARIE CURIEPRBB-CRG SessionsEva SchernhammerBrigham and Women's Hospital and Harvard Medical School"to be determined"Host: Manolis Kogevinas (CREAL)

09/10/201512:00MARIE CURIEPRBB-CRG SessionsRaphael KopanUniversity of Cincinnati. Ohio, United States"to be determined"Host: Anna Bigas (IMIM)

13/10/201512:00RAMÓN Y CAJALPRBB-CRG SessionsVittorio SartorelliMax Planck Research Group for RNA Biology, Max Planck Institute for Molecular Biomedicine, Múnster DE"Epigenetics of skeletal myogenesis"Host: Pura Muñoz-Canovas (UPF)

16/10/201512:00MARIE CURIEPRBB-CRG SessionsDan BenjaminCornell University, New York US"to be determined"Host: Arcadi Navarro (CRG)

19/10/201512:00MARIE CURIEPRBB-CRG SessionsDante ChiavoEstudios Multidisciplinarios en Sistemas Complejos y Ciencias del Cerebro, Buenos Aires AR"The mind near the edge: A novel view of brain function"Host: Jordi Garcia-Ojalvo (UPF)Abstract:Systems which are near an edge between order and disorder behave differently. This intuitive notion led several of us
to argue, two decades ago, that the most fundamental properties of the functioning brain are only feasible because it is spontaneously located at the border of an instability. It is the mix of order and disorder found generically at criticality that allows the brain to be a brain. In this talk we review the motivations and...

26/10/201512:00MARIE CURIEPRBB-CRG SessionsJavier BucetaLehigh University, Bethlehem US"Complex Dynamics in Multicellular Environments”Host: Jordi Garcia-Ojalvo (UPF)Abstract:In this talk he will review our recent work in the field of multicellular systems. In particular he will introduce a gene regulatory network that induces a continuous phase transition that coordinates robustly the behavior of living matter at the level of a cell population. The building blocks of this design are a well-known synthetic circuit, the so-called toggle switch, interfaced with two modified quorum sensing modules, Las and Lux. He will show that above a value of the transport...

02/11/201512:00MARIE CURIEPRBB-CRG SessionsKonstantinos KonstantopoulosDepartment of Chemical & Biomolecular Engineering, Johns Hopkins Whiting School of Engineering. Baltimore, US"A Bioengineering Perspective on Cell Locomotion"Host: Miguel Àngel Valverde (UPF)Abstract:Cell migration is a fundamental process underlying diverse (patho)physiological phenomena, including cancer metastasis. Much of what we know about the mechanisms of cell locomotion stems from in vitro studies using two-dimensional (2D) substrates. Cell locomotion in 2D is driven by cycles of actin protrusion, integrin-mediated adhesion and myosin-dependent...

06/11/201512:00CHARLES DARWINPRBB-CRG SessionsAnthony HymanMax Planck Institute of Molecular Cell Biology and Genetics, Dresden DE"to be determined"Host: Ben Lehner (CRG)

09/11/201512:00MARIE CURIEPRBB-CRG SessionsRamon LatorreUniversidad Valparaiso CL"to be determined"Host: Miguel Ángel Valverde (UPF)

16/11/201512:00RAMÓN Y CAJALPRBB-CRG SessionsSpyretta GolematiFirst Intensive Care Unit, Medical School, National Kapodistrian University of Athens, Athens, Greece"Ultrasound image analysis of the carotid artery: a powerful tool toward early stroke prediction and more than that"Host: Esther Barreiro (IMIM)

20/11/201512:00CHARLES DARWINPRBB-CRG SessionsMichael EisenHoward Hughes Medical Institute, University of California at Berkeley, Berkeley US"to be determined"Host: Roderic Guigó (CRG)

23/11/201512:00PRBB AuditoriumPRBB-CRG SessionsMichael LevittStanford University School of Medicine, Stanford, CA, USA"to be determined"Host: Josefa Gonzalez Perez (IBE)

27/11/201512:00MARIE CURIEPRBB-CRG SessionsJuan Martin SerranoDepartment of Infectious Diseases, King's College London School of Medicine at Guy's, King's and St Thomas' Hospitals, London UK"to be determined"Host: Manuel Mendoza (CRG)

04/12/201512:00MARIE CURIEPRBB-CRG SessionsKaterina PolitiYale School of Medicine, US"to be determined"Host: Michela Bertero (CRG)

11/12/201512:00MARIE CURIEPRBB-CRG SessionsJohn McGannPsychology Department Rutgers, The State University of New Jersey US"to be determined"Host: Mathieu Louis (CRG)

14/12/201512:00MARIE CURIEPRBB-CRG SessionsCaroline ReltonUniversity of Bristol UK"to be determined"Host: Mariona Bustamante (CREAL)

21/12/201512:00MARIE CURIEPRBB-CRG SessionsGabriel RabinovichInstitute of Experimental Biological Medicine, Buenos Aires, Argentina"to be determined"Host: Pilar Navarro (IMIM)