CRG Scientific Sessions

11/07/202512:00MARIE CURIEPRBB-CRG SessionsMichael RosbashDepartment of Biology, Brandeis UniversityLeveraging Drosophila circadian biology reveals a neurodegeneration-aging-cancer connectionHost: Juan ValcárcelAbstract:I will describe some lessons learned (and others still not learned) during my long career, and I will then segue to circadian rhythms with an emphasis on personal history and neuroscience. I will spend about the last half of the time on recent experiments from my lab that are responsible for the enigmatic title.

26/09/202512:00MARIE CURIEPRBB-CRG SessionsElinor KarlssonVertebrate Genomics Group at the Broad Institute of MIT and Harvard"TBC"Host: Donate Weghorn

17/10/202512:00MARIE CURIEPRBB-CRG SessionsMichael HillerLOEWE Centre for Translational Biodiversity GenomicsLinking phenotypic differences between species to differences in their genomesHost: Manuel IrimiaAbstract:In the first part of the talk, I will present TOGA (Tool to infer Orthologs from Genome Alignments) version 2.0, the completely reimplemented successor to the original method that simultaneously annotates coding genes and infers orthologs. TOGA 2.0 provides several new features, among them deep learning-based splice site predictions, which enable the method to cope with exon boundary shifts and evolutionary exon-intron structure changes.

In the...