Thursday, 27 September
09:15-09:30 Welcome by Luis Serrano, CRG Director
Welcome by the organizers (CRG PhD and Postdocs organizer committee)
Session 1 - Molecules in high resolution
It is perhaps modern imaging technologies that have had the strongest impact on the field of cell biology, and will unquestionably continue to do so. The trend is to label and monitor molecules, organelles and cells and their interactions, using increasingly sophisticated tools, in real time. These images are beginning to change our views of the dynamic nature of some of the most fundamental cell biological processes.
09:30-10:10 "High resolution structure determination of dynamic macromolecular complexes by cryo-EM"
Holger STARK, Max Planck Institute for Biophysical Chemistry, Göttingen, DE
10:10-10:25 Selected talk
10:25-11:00 Networking Café
11:00-11:40 “to be determined”
Ibrahim CISSÉ, MIT Department of Physics, Cambridge, US
11:40-11:55 Selected talk
11:55-12:35 "High throughput localization microscopy for structural determination"
Suliana MANLEY, École Polytechnique Fédérale de Lausanne, CH
12:35-13:15 Round table
13:15-14:30 Lunch & Poster session
14:30-14:10 “to be determined”
Ralf JUNGMANN, Max-Planck-Institut für Biochemie, DE
Session 2 - The inner life of the cell (I)
More and more scientists are jumping into single-cell analysis, which spans classical cell biology, developmental biology, genomics and computational biology. As the technologies to study single cells expand, they will require sophisticated analytical tools to get the data and make sense of results. Without doubt, single-cell analysis will open new vistas for scientists to explore.
14:10-15:25 Selected talk
15:25-16:05 “to be determined”
Jeannie LEE, Department of Genetics, Harvard Medical School, Boston, US
16:05-17:15 Poster session Café
17:15-17:30 Selected talk
17:30-18:10 “to be determined”
Melina SCHUH, Max Planck Institute for Biophysical Chemistry, Göttingen, DE
18:10-19:30 “Big Van” Show talk
19:30 Chat & Tapas
Friday, 28 September
Session 3 - Genome and organoid engineering
Organoids – the 3D self-organizing structures produced in vitro from pluripotent or somatic stem cells that show realistic micro-anatomy – can recapitulate many aspects of structural organization and functionality of their in vivo organ counterparts, thus holding great promise for biomedical research and translational applications. Importantly, faithful recapitulation of disease and development processes relies on the ability to modify the genomic contents in organoid cells. The revolutionary genome engineering technologies, including CRISPR/Cas9, is enabling investigators to generate various reporter cell lines at a fast pace for screening disease-associated mutations for disease modeling as well as for validation of specific cell lineages.
09:00-09:40 “to be determined”
Jürgen KNOBLICH, IMBA – Institute of Molecular Biotechnology, Vienna, AT
09:40-09:55 Selected talk
09:55-10:30 Networking café
10:30-11:10 “Building cancer in organoids”
Marc van de WETERING, Hubrecht Institute, Utrecht, NL
11:10-11:25 Selected talk
11:25-12:05 “to be determined”
Osamu NUREKI, Graduate School of Science, The University of Tokyo, JP
12:05-12:45 Round table
12:45-13:45 Lunch & Poster Session
Session 4 - Building and understanding complex systems
Synthetic biology, the convergence of advances in chemistry, biology, computer science, and engineering, is a biology-based “toolkit” that uses abstraction, standardization, and automated construction to change how we build biological systems and expand the range of possible products. Its breakthroughs will speed the development of biologically engineered solutions to pressing global problems related to health, materials, energy, environment, and security.
13:45-14:25 “to be determined”
Pamela SILVER, Harvard Medical School, Boston, US
14:25-14:40 Selected talk
14:40-15:20 "Synthetic Virology: Reprogramming viruses into controllable nanodevices"
Junghae SUH, Department of Bioengineering, Rice University, Texas, US
15:20-15:45 Coffee break
15:45-16:00 Selected talk
16.00-16:40 “to be determined”
Tom ELLIS, Imperial College of London, UK
16:40-17:20 "Phase separation in cells and its implications for organization of cellular biochemistry"
Anthony HYMAN, Max Planck Institute of Molecular Cell Biology & Genetics, Dresden, DE
17:20 Prize to the best Oral talk & Poster
17:30 Closing remarks by the organizers