Biomolecular Screening & Protein Technologies Unit
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Head of the Biomolecular Screening and Protein Technologies Unit
CRG-Centre for Genomic Regulation
Room 512 (5th floor)
Tel. +34 93 316 02 66
Since July 2013: Head of the Biomolecular Screening & Protein Technologies Facility, CRG, Barcelona, Spain
2010-2013: Senior Technical Officer, Biomolecular Screening & Protein Technologies Facility, CRG, Barcelona, Spain
2008-2010: Postdoctoral researcher, Structural and Computational Biology Programme, IRB, Barcelona, Spain
2008: Postdoctoral researcher, EMBL, Heidelberg, Germany
2007: PhD in Structural Biology, EMBL, Heidelberg, Germany
The scope of the Biomolecular Screening & Protein Technologies Unit (BMS-PT) is to provide researchers at CRG/PRBB and external institutions with a state-of-the-art technology platform and broad knowledge and expertise to perform medium to high-throughput RNA interference assays, chemical screenings, protein engineering and biophysical characterization of proteins and nucleic acids.
Part of the available equipment is endowed with various degrees of automation and utilized for a variety of molecular biology, biophysics and screening applications comprising the preparation of expression vectors, screening of diverse expression conditions, protein purification on a milligram scale and biophysical analysis. In addition, biochemical, cellular and image-based high content screening assays can be performed.
The BMS-PT Unit also collaborates in scientific projects funded by the European Commission 7th Framework Programme. One such project is PROSPECTS (PROteomics SPECification in Time and Space, http://www.prospects-fp7.eu/) whose goal is to annotate quantitatively the human proteome with respect to protein localization and dynamics. The project aims to make a major advance in the field both by developing more powerful instrumentation and by applying novel proteomics methods.
Another collaborative project is the SysteMTb project for the establishment of a systems biology framework to understand key features of Mycobacterium tuberculosis (http://www.systemtb.org). The SysteMTb project aims at providing a rational framework to understand mycobacterial physiology during infection and to identify essential nodes that are optimal for effective therapeutic interventions.