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CRG Scientific Sessions

CRG Scientific Sessions

21/09/201812:00MARIE CURIEPRBB-CRG SessionsJohannes SödingMax Planck Institute for Biophysical Chemistry, München, DE"New algorithms and tools for large-scale sequence analysis of metagenomics data"Host: Roderic Guigó (CRG)Abstract:Sequencing costs have dropped much faster than Moore's law in the past decade. The analysis of large metagenomic datasets and not their generation is now the main time and cost bottleneck. We present three methods that together allow us to move from an experiment-by experiment analysis to large-scale analyses of hundreds or thousands of metagenomic datasets.

MMseqs2 [1] is a protein sequence and profile search method slightly more...

25/09/201810:00PRBB AuditoriumPRBB-CRG SessionsXiang-Dong FuDivision of Cellular and Molecular Medicine, University of California, San Diego, USA"Repairing Damaged Brain by Replenishing Lost Neurons via in situ Trans-differentiation"Host: Juan Valcárcel (CRG) and Vivek Malhotra (CRG)Abstract:Parkinson disease is characterized by loss of dopamine neurons in the substantia nigra. As with other neurodegenerative diseases, no disease-modifying treatments exist. Important treatment objectives are to prevent neuronal loss to protect vulnerable neuronal circuits or to replace lost neurons to reconstruct disrupted circuits. To explore the second strategy, we show that isolated mouse and...

27/09/201812:00PRBB AuditoriumPRBB-CRG SessionsJeannie LeeDepartment of Molecular Biology, Massachusetts General Hospital"to be determined"Host: Bernhard Payer (CRG)

05/10/201812:00MARIE CURIEPRBB-CRG SessionsShobha VasudevanMGH, Harvard University US"A specialized post-transcriptional program in chemoresistant, quiescent cancer cells"Host: Fátima Gebauer (CRG)Abstract:Quiescent (G0) cells are a clinically relevant fraction in cancers, which include dormant cancer stem cells, and resist clinical therapy. G0 cells reveal extensive changes in gene expression at the protein and translation levels. We previously identified that the translation mechanism is altered in G0 cancer cells. MicroRNAs, noncoding RNAs that target distinct mRNAs to alter gene expression—were found to associate with a key RNA-binding protein, and...

08/10/201810:00CHARLES DARWINGene Regulation,Stem Cells&Cancer Progr.Ivano MocaviniLuciano Di Croce Lab. / Miguel Beato Lab."A role for RNA in PRC2 activity: recruitment or eviction?"Host: Pérez González, Gemma

08/10/201812:00MARIE CURIEPRBB-CRG SessionsBert BrunekreefInstitute for Risk Assessment Sciences, Utrecht, NL"Quantifying the air pollution burden of disease"Host: Josep M. Antó (ISGlobal)

15/10/201810:00CHARLES DARWINGene Regulation,Stem Cells&Cancer Progr.Estefania ManciniJuan Valcarcel Lab."Reconstruction of alternative splicing regulatory networks"Host: Pérez González, Gemma

19/10/201812:00MARIE CURIEPRBB-CRG SessionsMaya SchuldinerWeissman Institute, IL"Systematic approaches to study the many ways to target proteins to the secretory pathway"Host: PhD Students (CRG)Abstract:The evolutionary emergence of organelles was a defining process in diversifying biochemical reactions within the cell and enabling multi-cellularity. However, compartmentalization also posed a great challenge - the need to import proteins synthesized in the cytosol into their respective sites of function. For example, one third of all cellular proteins must be targeted and translocated into the endoplasmic reticulum (ER), which serves as the entry site into the...

22/10/201812:00MARIE CURIEPRBB-CRG SessionsClaudi SternDeparment of Cell & Development Biology, University College London, UK"to be determined"Host: Berta Alsina (UPF)

24/10/201810:00CHARLES DARWINGene Regulation,Stem Cells&Cancer Progr.Ivan TopisirovicInvestigator, Lady Davis Institute,SMBD Jewish General Hospital Associate Professor, Dept of Oncology, McGill University. Montreal"Translational regulation of metabolic plasticity in neoplasia"Host: Gebauer Hernández, Fátima

26/10/201812:00MARIE CURIEPRBB-CRG SessionsAndrea PauliResearch Institute of Molecular Pathology, Vienna, AT"Small proteins with big roles – from coordinating cell migration to mediating species-specific fertilization"Host: Verena Ruprecht (CRG)Abstract:Many transcripts have recently been found to contain short translated open reading frames that had been missed in previous gene annotations. A main focus of the Pauli lab is the identification of novel functional short proteins, using zebrafish as a model system. The Pauli lab has discovered two essential short proteins which differ in their biological functions: Toddler/Apela/ELABELA is a secreted peptide...

05/11/201812:00MARIE CURIEPRBB-CRG SessionsSalah El MestilkawyInstitution/Department McGill University, Department of Psychiatry, CA"Regulation of the striatum by cholinergic interneurons: implication of addiction and eating disorders"Host: Rafael Maldonado (UPF)

07/11/201812:00R_473.10_AULACell and Developmental Biology ProgrammeChii Jou ChanSymmetry breaking and self-organisation, EMBL HeidelbergTBCHost: Carbonell García, Rut

16/11/201812:00MARIE CURIEPRBB-CRG SessionsKen ZaretPerelman School of Medecine, University of Pennslvania, US"Overcoming Chromatin Barriers to Change Cell Fate"Host: Thomas Graf (CRG)Abstract:Kenneth S. Zaret, Ryan McCarthy, Kelsey Kaeding, Greg Donahue, Dario Nicetto
Institute for Regenerative Medicine, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, U.S.A

The incredible diversity of animals and plants depends upon embryonic cells to differentiate into various cell types and to stably retain such differentiation after development. In the future, we will be able to control...

23/11/201812:00MARIE CURIEPRBB-CRG SessionsEugene YeoUCSan Diego, US"to be determined"Host: PhD Students

14/12/201812:00MARIE CURIEPRBB-CRG SessionsJuan Antonio VizcainoEuropean Bioinformatics Institute - EMBL-EBI, Cambridge, UK"to be determined"Host: Eduard Sabidó (CRG)

17/12/201812:00MARIE CURIEPRBB-CRG SessionsLluis MoreyUniversity of Miami, Miller School of Medicine, Miami USA"to be determined"Host: Luciano di Croce (CRG)

11/01/201912:00MARIE CURIEPRBB-CRG SessionsTiziana BonaldiInstituto Europeo di Oncologia, Milan, IT"to be determined"Host: Eduard Sabidó (CRG)

18/01/201912:00MARIE CURIEPRBB-CRG SessionsAlexander van OudenaardenHubrecht Institute, Utrech NL"to be determined"Host: Ben Lehner (CRG)

08/02/201912:00MARIE CURIEPRBB-CRG SessionsCarl-Philipp HeisenbergInstitute of Science and Technology, AT"to be determined"Host: Verena Ruprecht (CRG)

15/02/201912:00MARIE CURIEPRBB-CRG SessionsClaudia BagniDépartment des neurosciences fondamentales, Université de Lausanne, CH"to be determined"Host: Juan Valcárcel (CRG)

12/07/201912:00MARIE CURIEPRBB-CRG SessionsTrisha WittkoppU-M LSA Ecology and Evolutionary Biology (EEB), USA"to be determined"Host: PhD Students

06/09/201912:00MARIE CURIEPRBB-CRG SessionsNathalie BalabanThe Hebrew University of Jerusalem, IL"to be determined"Host: Lucas Carey (UPF) and Ben Lehner (CRG)