CRG Scientific Sessions
12/12/201711:00R_473.10_AULAGene Regulation,Stem Cells&Cancer Progr.Cornelia H. de Moor, PhDSchool of Pharmacy Building. University Park. Nottingham NG7 2RD. UK“Polyadenylation as a therapeutic target for cancer and inflammatory diseases”Host: Gebauer Hernández, Fátima
12/12/201715:00R_473.10_AULASystems Biology ProgrammeLorea BlazquezDEPARTMENT OF MOLECULAR NEUROSCIENCE. UNIVERSITY COLLEGE LONDON. RNA NETWORKS LAB. THE FRANCIS CRICK INSTITUTE“A recursive mechanism of alternative splicing regulated by the Exon Junction Complex”Host: Irimia Martínez, ManuelAbstract:Recursive splicing (RS) allows removal of introns in a two-step process. This requires definition of a ‘RS-exon’, which reconstitutes a new 5’ splice site (RS-5ss) after its splicing to the preceding exon. We have found that over 5% of human annotated exons can reconstitute a RS-5ss. While most of these annotated RS-exons are constitutive, many of them become skipped upon perturbation of the Exon Junction Complex (EJC). EJC represses...
19/12/201712:00R_473.10_AULACell and Developmental Biology ProgrammeMonica Bettencourt DiasCell Cycle Regulation. IGC - Instituto Gulbenkian de Ciência"Centrosomes and Cilia in Development & Disease"Host: Vernos, IsabelleAbstract:Centrioles are microtubule-based cylinders that are critical to form centrosomes and cilia.
The centrosome is the major microtubule organising center in animal cells, while cilia are critical for a variety of functions, from signalling to cellular motility.
Most studies have so far been focused on core mechanisms of the assembly and function of these structures.
In my talk I will discuss how these structures are shaped differently in different tissues so that they can perform many...
28/05/201812:00MARIE CURIEPRBB-CRG SessionsFernando BenavidesLaboratiory Animal Genetic Services, Department of Epigenetics and Molecular Carcinogenesis, MD Anderson Cancer Center, The University of Texas, USA"Inbred mice, similar but different (the devil is in details)Host: Juan Martín-Caballero (PRBB)