CRG Scientific Sessions
23/11/201812:00MARIE CURIEPRBB-CRG SessionsEugene YeoUCSan Diego, US"RNA binding proteins: Engineers of Human Health"Host: PhD StudentsAbstract:RNA processing defects underlies a multitude of human diseases, including neurodegeneration and cancer. RNA metabolism is mediated by RNA binding proteins encoded in the human genome, I will present several topics: (1) our large-scale studies of human RNA binding proteins using enhanced CLIP and integrative analyses with orthogonal genome-wide methodologies, (2) our recent interests in RNA granules in the context of neurodegeneration and (3) our efforts in RNA-targeting CRISPR therapeutics.
26/11/201815:00CHARLES DARWINBioinformatics and Genomics ProgrammeBjörn Langer (postdoc candidate)Center for Systems Biology Dresden / Max Planck Institutes of Molecular Cell Biology and GeneticsLinking complex phenotypic changes to the divergence of the gene-regulatory landscapeHost: Notredame, CedricAbstract:A key component of gene regulation is the interaction of transcription factors and regulatory regions of a gene. Changes in gene regulatory regions alter the binding affinities of the transcription factors to them and thus influence gene expression. Such gene expression changes are assumed to be the main cause of the evolution of morphological and other complex phenotypic traits. Nevertheless, for most complex phenotypes our...
03/12/201813:00R_473.10_AULAGene Regulation,Stem Cells&Cancer Progr.Laura Soto. PhD CandidateInstitute of Pharmacology, University of Marburg, Germany"MRTF/SRF transcription promotes Ezrin-dependent bleb-associated invasion"Host: Cosma, Maria Pia