CRG Scientific Sessions
02/07/202612:30PRBBGene Regulation,Stem Cells&Cancer Progr.Boxuan ZhaoUniversity of IllinoisMapping the Communicatome: RNA-Barcoding Technologies to Decode Cell-Cell Connections at Single-Cell ResolutionHost: Tagliaferro, BarbaraAbstract:How cells communicate, whether through synapses, contact-dependent signals, or secreted factors, underlies diverse biological processes ranging from neural circuit function to tumor progression. Yet for many cell-cell connections, the identity of the partners involved and the molecular content of those interactions remain poorly characterized, in part because tools for systematically resolving connectivity at the level of single cells have been limited. We are developing a suite of sequencing-...
03/07/202612:00MARIE CURIEPRBB-CRG SessionsMaria BarnaStanford Medicine"Ribosomes in Gene Regulation: Controlling Protein Diversity Across Cells, Tissues and Organisms"Host: Fatima GebauerAbstract:Ribosomes have traditionally been viewed as uniform machines that execute protein synthesis, yet growing evidence suggests that they can act as specialized regulators of gene expression. In this talk, I will discuss how new technologies from our lab have revealed unexpected biological roles for ribosomes in controlling protein diversity across cells and tissues. Using RiboExM and ALIBI, we find that ribosomes are not evenly distributed or compositionally uniform, but...
16/07/202610:00CHARLES DARWINOther SeminarsSheng-Hong ChenAcademia Sinica"The Spatial Logic of Cell Death: Ferroptotic Trigger Waves, Self-Organization, and Tissue Morphogenesis"Host: Lin, Hsiu-ChuanAbstract:Large-scale cell death is essential for tissue sculpting during development, yet how death events are coordinated across millimeter-scale tissues remains poorly understood. I will discuss our recent work revealing that ferroptosis, an iron- and lipid-peroxidation-dependent form of cell death, can propagate through cell populations as self-regenerating trigger waves of reactive oxygen species. These waves arise when ferroptotic stress converts cellular redox networks into bistable media, enabling local death events to spread over...
21/07/202612:00MARIE CURIEPRBB-CRG SessionsMark GersteinYale School of Medicine"Topics in Neurogenomics: Using AI to Study Endophenotypes & then Having it Take Over"Host: Silvia Perez-LluchAbstract:This talk explores the use of AI to study and eventually drive neurogenomics research. It covers linking wearable-derived "digital phenotypes" to genotype for conditions like ADHD, showing this approach uncovers SNPs missed by traditional case-control GWAS. It
then examines single-cell data (e.g., PsychENCODE's 388-brain dataset) to build cell-type-specific regulatory and cell-to-cell communication networks, integrating them into deep learning models that...
04/09/202612:00MARIE CURIEPRBB-CRG SessionsTaro KitazawaDANDRITE-Nordic-EMBL & Aarhus University"TBC"Host: Hsiu-Chuan Lin
18/09/202612:00MARIE CURIEPRBB-CRG SessionsAugustine KongOxford Big Data Institute"TBC"Host: Amelie Baud
07/10/202609:00RAMÓN Y CAJALOther SeminarsSymposio red RBP-RegunetGebauer Lab-Host: Tagliaferro, Barbara
23/10/202612:00MARIE CURIEPRBB-CRG SessionsElisa OricchioEPFL"TBC"Host: Renée Beekman
30/10/202612:00MARIE CURIEPRBB-CRG SessionsEmmanuel DeriveryMRC Laboratory of Molecular Biology"TBC"Host: Thomas Surrey & Adel Al Jord
04/12/202612:00MARIE CURIEPRBB-CRG SessionsChristine MayrMemorial Sloan Kettering Cancer Center"TBC"Host: Adel Al Jord