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09
Feb
The image shows pancreatic islets in mice, specialised tissues that host beta cells. On the left, a healthy pancreatic islet is shown with its typical morphology with alpha cells in the periphery and beta cells in the core of the islet. On the right, mice with a mutation in Srrm3 that knock out the cells’ ability to regulate microexon inclusion results in islets with altered morphology and cell identity. This and other functional alterations ultimately impacts on the release of insulin. Jonas Juan Mateu
‘Tiny but mighty’ gene fragments are crucial for maintaining blood sugar levels

Microexons constitute new potential therapeutic targets for treating diabetes

RESEARCH
31
Jan
Research exploring how human egg cells remain healthy for decades backed by ERC

Elvan Böke’s research group receives a 2-million-euro European Research Consolidator grant

FUNDING
19
Jan
This shows a cross-section of a mouse lung infected with Pseudonomas aeruginosa. The mouse was treated with a version of Mycoplasma pneumoniae that could not produce therapeutic molecules, resulting in severe pneumoniae. This is characterised by massive infiltration of inflammatory cells into the alveolar septa, resulting in loss of air in the alveoli. Credit: Rocco Mazzolini/CRG
‘Living medicine’ created to tackle drug-resistant lung infections

Study showcases synthetic biology's potential in transforming treatment of human disease

RESEARCH
28
Dec
Human diabetes risk influenced by genomic regulation of RNA splicing

RNA splicing regulation influences transcription of genes inked to type-1 and type-1 diabetes risk

RESEARCH
14
Dec
Pulmobiotics receives 1.9m euros to develop ‘living medicine’ for lung cancer

European Innovation Council backs CRG start-up to further efforts in treating leading cause of cancer mortality worldwide
28
Nov
Image 1. Mitotic spindles with microtubules (red) attached to chromosomes (blue) during cell division. Cells with normal TTLL11 function (right) have normal rates of microtubule polyglutamylation (green) while cells without TTLL11 (left) are unmodified. Isabelle Vernos
Cell division enzyme earmarked as potential new cancer therapeutic target

The enzyme’s activity was found to be compromised in human cancer cells

RESEARCH
24
Nov
CRG receives Next Generation EU funds for cancer research

Luciano Di Croce and Isabelle Vernos will identify and validate new therapeutics targets for breast cancer and midline gliomas

FUNDING
23
Nov
Milner Therapeutics Institute leads pharma partner visit to IRB Barcelona and CRG

Visit aimed to foster collaboration between pharma companies and research centres
22
Nov
CRG researchers selected for EMBO Young Investigator programme

Lars Velten and Arnau Sebe Pedros have been recognised by the prestigious organisation

HONOURS & AWARDS
27
Oct
Image of a mouse pancreatic islet, regions in the pancreas that contain beta cells which secret insulin. The HASTER regulatory element has been knocked out in this mouse, resulting in changes to beta cell function that cause diabetes. Credit: Miguel A Garriga/
Diabetes-causing gene can be regulated like a rheostat

Studying noncoding RNAs opens new avenues to understand human disease 

RESEARCH

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